{"id":136,"date":"2021-11-19T21:13:12","date_gmt":"2021-11-19T20:13:12","guid":{"rendered":"http:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/?page_id=136"},"modified":"2021-12-09T20:40:40","modified_gmt":"2021-12-09T19:40:40","slug":"alexis-bernartets","status":"publish","type":"page","link":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/?page_id=136","title":{"rendered":"Alexis BERNATETS"},"content":{"rendered":"\n<div class=\"wp-block-media-text alignwide is-stacked-on-mobile\" style=\"grid-template-columns:30% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" width=\"510\" height=\"637\" src=\"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/wp-content\/uploads\/2021\/11\/alexis.jpg\" alt=\"\" class=\"wp-image-137\" srcset=\"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/wp-content\/uploads\/2021\/11\/alexis.jpg 510w, https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/wp-content\/uploads\/2021\/11\/alexis-240x300.jpg 240w\" sizes=\"(max-width: 510px) 100vw, 510px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"has-text-align-left\"><em>Doctorant Chercheur<\/em> | ENS Paris Saclay &#8211; INSERM UMR-S 1193 &#8211; Chimie ParisTech<\/p>\n\n\n\n<p><a href=\"https:\/\/www.universite-paris-saclay.fr\/en?search_api_fulltext=&amp;page=4\">University Paris-Saclay<\/a><br><a href=\"https:\/\/ens-paris-saclay.fr\/en\">ENS Paris Saclay<\/a><br><a href=\"https:\/\/www.lumin.universite-paris-saclay.fr\/en\">CNRS LUMIN<\/a><br><a href=\"http:\/\/intrawww.satie.ens-cachan.fr\/Equipes\/BIOMIS\/BLPgroup_version2019\/BIOMIS\/index.html\">BIOMIS<\/a><br>4 avenue des sciences<br>91190 Gif sur Yvette, France<\/p>\n\n\n\n<p>Bureau 3X30, d&#8217;Alembert Institute<\/p>\n<\/div><\/div>\n\n\n\n<h3>PhD project summary<\/h3>\n\n\n\n<p>The production of organoid from induced pluripotent stem cells (iPSC) allows to reproduce all the complexity of a human tissue in vitro. Though, it is not possible yet to assess the health of such tissue. The project will aim at integrating a liver organoid into a microfluidic organ-on-a-chip-like system. The resulting organoid-on-a-chip will be both vascularized and drained by thesystem. The integration of microsensor in the chip itself will then grant us access to the monitoring of the organoid. This monitoring will be close to what is done by physicians during clinical studies. Hence the use of the organoid on an monitored chip as a tool for the study of drug induced hepatotoxicity, at the end of the project.<\/p>\n\n\n\n<p>This multi-expertise project is made possible by the collaboration of three laboratories. The culture of organo\u00efds from iPSC will be done with the help of INSERM UMR-S 1193, the design and fabrication of microfluidic chips with Institut d&#8217;Alembert (ENS Paris Saclay), and all the biosensors needed for the monitoring with Chimie ParisTech<\/p>\n\n\n\n<h3>Curriculum<\/h3>\n\n\n\n<ul><li>may 2021 &#8211; nov 2021 | Poietis | Intership, working on the bioprinter prototype of the company. Creating new protocole to handle the cellular ink, which physical and chemical properties vary strongly over time.<\/li><li>2020-2021 | Institut de formation sup\u00e9rieur au biom\u00e9dical (IFSBM) | Secondary Diploma in bioengineering<\/li><li>2016-2021 | \u00c9cole Centrale Paris | French Engineering School<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Doctorant Chercheur | ENS Paris Saclay &#8211; INSERM UMR-S 1193 &#8211; Chimie ParisTech University Paris-SaclayENS Paris SaclayCNRS LUMINBIOMIS4 avenue des sciences91190 Gif sur Yvette, France Bureau 3X30, d&#8217;Alembert Institute PhD project summary The production of organoid from induced pluripotent stem cells (iPSC) allows to reproduce all the complexity of a human tissue in vitro. Though, [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_expiration-date-status":"","_expiration-date":1639078772,"_expiration-date-type":"draft","_expiration-date-categories":[],"_expiration-date-options":[]},"_links":{"self":[{"href":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/index.php?rest_route=\/wp\/v2\/pages\/136"}],"collection":[{"href":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=136"}],"version-history":[{"count":2,"href":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/index.php?rest_route=\/wp\/v2\/pages\/136\/revisions"}],"predecessor-version":[{"id":211,"href":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/index.php?rest_route=\/wp\/v2\/pages\/136\/revisions\/211"}],"wp:attachment":[{"href":"https:\/\/hebergement.universite-paris-saclay.fr\/biomis_d\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=136"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}