One recurring difficulty in ecotoxicological studies is that a substantial portion of concentrations are below the limits of detection established by analytical laboratories. This results in censored distributions in which concentrations of some samples are only known to be below a threshold. The currently available methods have several limitations because they cannot be used with complex situations (e.g., different lower and upper limits in the same dataset, mixture of distributions, truncation and censoring in a single dataset). We propose a versatile method to fit the most diverse situations using conditional likelihood and Bayesian statistics.

Salvat-Leal I, Cortés-Gómez AA, Romero D, Girondot M: New method for imputation of unquantifiable values using bayesian statistics for a mixture of censored or truncated distributions: Application to trace elements measured in blood of olive ridley sea turtles from mexico. Animals 2022, 2022(12):2919.